Hello. This is CELITA CLINIC in Seomyeon, Busan, with you from consultation to aftercare.
Many people worry about double chins, cheek fat, and stubborn body fat ahead of the upcoming summer or important schedules. While considering contouring injections to address facial fat that simply won't go away with exercise and diet alone, quite a few hesitate, thinking, "The swelling after the procedure is too severe, making daily life difficult," or "The pain is burdensome."
Now, it's time to complete a slim facial line by safely removing the fat cells themselves, without having to endure the burden of temporary size reduction or pain. We now unveil the 40th Korean new drug and next-generation fat reduction injection, 'NUVIJU', which overcomes the limitations of existing fat dissolving injections and enables comfortable management.
What is the Next-Generation Fat Reduction Injection NUVIJU?

NUVIJU is an injection that has proven its efficacy and safety through a large-scale Phase 3 clinical trial by Medytox and received approval from the Ministry of Food and Drug Safety (MFDS) for the indication of 'improving moderate to severe submental fat'.
Developed with Cholic Acid (CA) as its main ingredient for the first time in the world, it drastically reduced adverse reactions such as pain, swelling, and nodules that commonly appeared with the widely used Deoxycholic Acid (DCA) injections. It is a 4th-generation premium contouring solution that you can receive with greater peace of mind, as chemical excipients (benzyl alcohol, benzethonium chloride) that can cause skin irritation have been excluded.
NUVIJU's 3-Step Action Principle
STEP 01: A drug containing Cholic Acid (CA) is injected into the target area, the submental subcutaneous fat layer.
STEP 02: Through surfactant action, it destroys the lipid bilayer structure of the fat cell membrane, inducing fat cell lysis (dissolution).
STEP 03: The destroyed fat cells are phagocytized by macrophages and naturally excreted as body waste such as sweat or urine, while inducing collagen synthesis in the empty spaces to prevent skin sagging.
3 Unique Advantages of NUVIJU That Make a Difference
Key Feature | Description & Expected Effect |
|---|---|
Direct Destruction of Fat Cells | It doesn't just simply reduce the size; it damages the fat cell membrane to decrease the number of cells. The dissolved fat is excreted, resulting in less yo-yo effect. |
Physiological pH 7.4 Optimization | Custom-designed with an acidity similar to the human body's physiological environment, it significantly reduces pain and tissue irritation during the procedure. |
Safety-Enhanced Design | By excluding chemical excipients that can cause allergies and skin irritation, even those with sensitive skin can receive the procedure without burden. |

Why Choose 'NUVIJU'? Overwhelming Clinical Results and Comfort
Proven Double Chin Improvement Effect: As a result of a large-scale Phase 3 clinical trial, the proportion of patients whose submental fat improved by 1 grade or more reached 88.57% (compared to 32.43% in the placebo group), providing a powerful and definitive change.
Pain and Stress Reduction: Additional non-clinical trials confirmed that blood stress hormone levels and the expression of pain receptors in skin tissue were significantly lower during subcutaneous injection, enabling comfortable management.
2-in-1 Procedure that Captures Elasticity: By inducing collagen generation in the location of the destroyed fat tissue, it prevents sagging of the jawline that may be a concern after fat loss and helps maintain an elastic V-line.
We Recommend It to These People
Those who are worried about localized fat (double chin, cheek fat, etc.) that won't go away with diet or exercise alone.
Those who experienced discomfort due to severe pain, swelling, or bruising after previous contouring injection procedures.
Those who need a quick return to daily life, such as going to work or attending appointments the day after the procedure.
Those who want a refined and slim contour line without bone-cutting surgical methods.
Those who want natural elasticity maintenance along with facial line improvement.
Procedure Process and Side Effects Guide
NUVIJU is a relatively comfortable procedure, but for safe and optimized results, please note the following:
Swelling and Stiffness: There may be swelling, bruising, and stiffness due to injection needle marks or drug reactions after the procedure, but it recovers naturally within 2~3 days. (Cold compresses are recommended.)
Temporary Redness: Skin redness is a temporary symptom that subsides within a few hours.
For safe and natural facial lines, it is crucial to receive the procedure from an experienced medical professional who accurately understands the structure of muscles and fat and can meticulously design a customized dosage.
Why Seomyeon, Busan, and CELITA CLINIC?
CELITA CLINIC is located near Exit 15 of Seomyeon Station. To maximize the effects of the next-generation fat reduction injection NUVIJU and increase patient satisfaction, we adhere to the following principles:
Objective pre-analysis of fat distribution and elasticity loss through the Eve V MUSE AI skin analysis device.
1:1 customized detailed design considering each individual's facial contour balance and fat thickness.
Strict adherence to using genuine NUVIJU in exact dosages, and confirming unboxing before the procedure.
Transparent pricing guide inclusive of VAT (Responses available in Japanese, Chinese, and English in addition to Korean).
Frequently Asked Questions (FAQ)
Q. What is the biggest difference between existing general contouring injections (fat dissolving injections) and NUVIJU?
A. The biggest difference lies in the 'ingredients' and 'minimization of side effects'. Existing products mainly used Deoxycholic Acid (DCA), which often accompanied pain during the procedure and severe swelling and bruising afterward. On the other hand, NUVIJU is the world's first to use Cholic Acid (CA) and optimizes the acidity (pH 7.4) to suit the human body, significantly lowering pain and swelling.
Q. When do the effects of NUVIJU appear, and how long do they last?
A. As the destroyed fat cells are gradually excreted from the body, you can feel a gradual size reduction effect starting about 1~2 weeks later. Because it directly removes the cells themselves rather than just reducing their size, the slim contour is maintained for a relatively long period with minimal yo-yo effect, provided there is no rapid weight gain.
Q. How much pain or swelling is there during the procedure?
A. Thanks to the ingredient formulation that lowers the expression of pain-related receptors, it is much less painful compared to existing DCA preparations, and you can receive it comfortably with numbing cream before the procedure. Post-procedure swelling is also significantly reduced, relieving worries like, "Is it okay to go to work the next day?"
Q. What are the recommended procedure intervals and frequency?
A. While it varies depending on the individual's fat amount and thickness, you can generally expect the most satisfactory V-line effect when you receive repeated procedures 3 to 4 times or more at 2 to 4-week intervals. The procedure plan will be guided as a customized fit through a 1:1 consultation upon your visit.
Q. Does skin sagging occur after the procedure?
A. NUVIJU has a feature that naturally induces collagen synthesis during the fat cell lysis process. This helps fill the space where fat has been removed with elasticity, preventing double chin sagging or skin laxity that might be a concern after the procedure. If you want a synergistic effect, we also recommend combination procedures with Botulinum Toxin (such as Coretox).
Q. Are there any special precautions or side effects after the procedure?
A. To allow the drug to work well, you should avoid strong rubbing or pressing massages on the treated area for 7 days. To prevent inflammation, please refrain from excessive drinking, smoking, saunas, and strenuous exercise for about a week, and we recommend drinking plenty of water to help excrete waste. Temporary redness or stiffness will disappear within a few days, so you can rest assured.
Reservation & Inquiries
You can book a free consultation or check out our ongoing events and packages via WhatsApp. The CELITA CLINIC team will assist you with everything from planning your visit to providing pre- and post-procedure guidance.
Precautions
This content was written for informational purposes and cannot substitute for medical advice. Results may vary depending on individual body constitution and fat amount, so please ensure you thoroughly consult with a qualified medical professional before the procedure to select the method that is appropriate for you.